What Is B12?
Vitamin B12 is a crucial nutrient that plays a significant role in energy production, DNA synthesis, brain and nervous system function, and the formation of red blood cells. It also contributes to heart health by helping to break down homocysteine, an amino acid linked to poor cardiovascular health. Since our bodies can’t produce this vitamin, we need to get it from our diet.
Vitamin B12 Metabolic Pathway
For the body to absorb B12, it relies on a glycoprotein called intrinsic factor, which is produced by the stomach’s parietal cells and salivary glands. Intrinsic factor allows B12 to move through the stomach and into the small intestine. Once in the small intestine, intrinsic factor dissolves, and B12 binds with another protein, transcobalamin II, to enter the bloodstream.
Why Is Methylcobalamin Absorbed the Best?
Methylcobalamin is a natural, active form of vitamin B12 and is the main form circulating in the blood. It can quickly enter the bloodstream, although only about 1% of what is ingested is absorbed. Methylcobalamin is highly bioavailable because it requires minimal conversion and easily passes through all stages of B12’s metabolic pathway. Another form of B12, adenosylcobalamin, is also readily absorbed by the body.
Does Methylcobalamin Promote Better Health?
Methylcobalamin doesn’t need a methyl group from the body for absorption, which saves metabolic energy and cellular resources. Methyl groups are essential for stabilizing free radicals and removing toxins, so preserving these groups is vital. Methylation also helps protect the brain by reducing the impact of dietary glutamate, a non-essential protein that can cause neural damage. Thus, methylcobalamin helps the body retain its crucial methyl groups for detoxification and overall health support.
Added Benefits
Researchers have found that methylcobalamin is the preferred form of B12 supplementation for those concerned about kidney health. Additionally, a double-blind study has shown that methylcobalamin supports healthy sleep patterns.
One Final Thought
Vitamin B12 is essential for life. For those looking to supplement with B12, methylcobalamin offers an efficient option. Its ability to add methyl groups and support proper methylation makes it ideal for many who may already be dealing with a B12 deficiency. Combining methylcobalamin with adenosylcobalamin is considered by many to be the best and safest representation of naturally occurring vitamin B12. Consider taking a supplement like our Organic Vitamin B12, which provides an ideal serving of both. Have you used methylcobalamin or adenosylcobalamin? Please share how they’ve affected your life.
